Call your doctor right away if you or your child has itching, trouble breathing or swallowing, or any swelling of your hands, face, or mouth. Though unusual, moderate side effects of omeprazole have been reported by patients as well. I was put on Omeprazole last week (Thursday). I took it for just under 2 weeks and on Friday had a terrible allergic rash with welts and hives everywhere. Answer Question. Lvl2. Diagnosed GERD and prescribed the dreaded Omeprazole. IV Prednisone and Piriton. We studied 9 patients with adverse reactions to omeprazole. The experimental skin tests appeared to be helpful in identifying the cause of their allergic reactions, especially when the PPI was the cause. There is no good way to know ahead of time if a person is going to have a reaction. This article looks at its uses, dosage, and side effects, as … Common side effects of Prilosec include diarrhea, nausea, vomiting, headaches, rash, dizziness, nervousness, abnormal heartbeats, muscle pain, weakness, and infrequently, leg cramps and water retention. Stomach pain is a possible side effect of omeprazole. Pretty stressed about it. The phase IV clinical study is created by eHealthMe based on reports of 289,144 people who have side effects when taking Omeprazole from the FDA, and is updated regularly. Is it normal to have a reaction like this with Omeprazole. Summary: Allergies is reported only by a few people who take Omeprazole. Genetic screening revealed that the patient poorly metabolized omeprazole. The phase IV clinical study is created by eHealthMe based on reports of 289,144 people who have side effects while taking Omeprazole from the FDA, and is updated regularly. Some people have experienced reactions to omeprazole that closely mimic the symptoms of common allergy attacks such as skin rash, hives, and feelings of tightness in the chest. The presence of cross-reactivity between different members of the group is not clear. Photosensitivity reaction is found among people who take Omeprazole, especially for people who are female, 60+ old, have been taking the drug for < 1 month. In general Omeprazole and other ppi drugs are well tolerated. Prilosec (omeprazole) is a proton pump inhibitor (PPI) that is used to treat the symptoms of ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome.  Therefore, severe adverse reactions (allergic shock, rash and diarrhea) experienced by the patient were caused by the accumulation of omeprazole metabolites resulting from its slow metabolism in vivo. Allergic reaction to Omeprazole? Omeprazole is a common drug that some people take to treat heartburn, or acid reflux. Yes: Theoretically, a person could have an allergic reaction to any medication including omeprazole. However, if a reaction … Oral challenges using the culprit PPI resulted in symptoms of an allergic reaction when the skin test was positive, and there was over a 90% correlation between the skin test and the oral challenge. By Tuesday my torso was covered in little red spots with some slight itching. Omeprazole works by blocking gastric acid secretion in your stomach which reduces heartburn, ... you should alert your doctor right away as this may indicate an allergic reaction … Omeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics. Clinical symptoms appeared immediately in 8 patients and after … Although rare, anaphylactic reactions induced by proton pump inhibitors have been reported. Had swelling lips and decided to go to A&E. 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